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The Globalization of Traditional Medicines: Perspectives Related to the European Union Regulatory Environment Perspective

Werner Knoess, Jacqueline Wiesner

Engineering 2019, Volume 5, Issue 1,   Pages 22-31 doi: 10.1016/j.eng.2018.11.012

Abstract:

In the Member States of the European Union (EU), a harmonized legislation on medicinal products hasbeen enforced, which specifically defines herbal medicinal products and traditional herbal medicinalproducts.medicinal products.The standards defined by the EU herbal monographs of the Committee on Herbal Medicinal Products (HMPC

Keywords： Traditional medicine     Traditional Chinese medicine     Committee on Herbal Medicinal Products     Herbal medicines    

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The regulatory sciences for stem cell-based medicinal products

Bao-Zhu Yuan,Junzhi Wang

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 190-200 doi: 10.1007/s11684-014-0323-5

Abstract: Moreover, some stem cell-based products have been approved for marketing by different national regulatoryto be established or improved to more effectively evaluate quality, safety and efficacy of stem cell products

Keywords： stem cell-based medicinal products (SCMPs)     stem cell therapy (SCT)     safety     effectiveness     standards     guidelines    

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The South-to-North Water Diversion Project

Office of the South-to-North Water Diversion Project Construction Committee, State Council, PRC

Engineering 2016, Volume 2, Issue 3,   Pages 265-267 doi: 10.1016/J.ENG.2016.03.022

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IN VITRO ACTIVITY OF EXTRACTS OF FIVE MEDICINAL PLANT SPECIES ON PLANT PATHOGENIC FUNGI

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 635-644 doi: 10.15302/J-FASE -2020343

Abstract:

The antifungal effectiveness of extracts of five medicinal plant species was determined.potential as a new natural fungicide and may be used for the preservation of agricultural and forestry products

Keywords： Botrytis cinerea / food preservation / plant diseases / plant pathogenic fungi / Tupistra chinensis    

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An introduction to the medicinal plant genome project

Shilin Chen, Li Xiang, Xu Guo, Qiushi Li

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 178-184 doi: 10.1007/s11684-011-0131-0

Abstract: However, very few studies have been carried out on genomics for medicinal plants.This paper introduces the genome research of medicinal plants, including genome sequencing, assembly,

Keywords： genomics     medicinal plant     sequencing     application    

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Lingguizhugan Decoction, a Chinese herbal formula, improves insulin resistance in overweight/obese subjects

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 745-759 doi: 10.1007/s11684-021-0880-3

Abstract: Lingguizhugan Decoction (LGZG) has been investigated in basic studies, with satisfactory effects on insulin resistance in non-alcoholic fatty liver disease (NAFLD). This translational approach aimed to explore the effect and underlying mechanism of LGZG in clinical setting. A randomized, double-blinded, placebo-controlled trial was performed. A total of 243 eligible participants with NAFLD were equally allocated to receive LGZG (two groups: standard dose and low dose) or placebo for 12 weeks on the basis of lifestyle modifications. The primary efficacy variable was homeostasis model assessment of insulin resistance (HOMA-IR). Analyses were performed in two populations in accordance with body mass index (BMI; overweight/obese, BMI ≥ 24 kg/m2; lean, BMI < 24 kg/m 2). For overweight/obese participants, low-dose LGZG significantly decreased their HOMA-IR level compared with placebo (−0.19 (1.47) versus 0.08 (1.99),P = 0.038). For lean subjects, neither dose of LGZG showed a superior effect compared with placebo. Methylated DNA immunoprecipitation sequencing and real-time qPCR found that the DNA N6-methyladenine modification levels of protein phosphatase 1 regulatory subunit 3A (PPP1R3A) and autophagy related 3 (ATG3) significantly increased after LGZG intervention in overweight/obese population. Low-dose LGZG effectively improved insulin resistance in overweight/obese subjects with NAFLD. The underlying mechanism may be related to the regulation of DNA N6-methyladenine modification of PPP1R3A and ATG3. Lean subjects may not be a targeted population for LGZG.

Keywords： insulin resistance     non-alcoholic fatty liver disease     Chinese herbal medicine     randomized controlled    

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ACTIVITY OF EXTRACTS OF FIVE MEDICINAL PLANT SPECIES ON PLANT PATHOGENIC FUNGI

Shufeng YAO, Jiali XU, Haibo ZHANG, Hong GAO, Shibin SHANG, Dan WANG

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 635-644 doi: 10.15302/J-FASE-2020343

Abstract: The antifungal effectiveness of extracts of five medicinal plant species was determined.potential as a new natural fungicide and may be used for the preservation of agricultural and forestry products

Keywords： Botrytis cinerea     food preservation     plant diseases     plant pathogenic fungi     Tupistra chinensis    

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Screening of indicator pharmaceuticals and personal care products in landfill leachates: a case study

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 9, doi: 10.1007/s11783-023-1716-y

Abstract:

● A systematic framework was developed to identify i-PPCPs for landfill leachate.

Keywords： Landfill leachates     PPCPs     Indicator     Screening criteria     Source-specificity    

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Characteristics of typical dissolved black carbons and their influence on the formation of disinfection by-products

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 12, doi: 10.1007/s11783-022-1585-9

Abstract:

● The physicochemical and structural properties of DBC were characterized.

Keywords： Dissolved black carbon (DBC)     Chlorine     Chloramine     Disinfection by-products (DBPs)     Disinfection by-products    

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Antifungal and antibacterial functions of medicinal leech recombinant destabilase-lysozyme and its heated-up

T. G. YUDINA, Danyang GUO, N. F. PISKUNKOVA, I. B. PAVLOVA, L. L. ZAVALOVA, I. P. BASKOVA

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2,   Pages 203-209 doi: 10.1007/s11705-012-1277-2

Abstract: Antifungal activity of recombinant medicinal leech destabilase-lysozyme (rec.Dest-Lys) was investigated

Keywords： recombinant destabilase-lysozyme (rec.Dest-Lys)     antimicrobial activity     antifungal activity     medicinal    

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Data quality assessment for studies investigating microplastics and nanoplastics in food products: Are

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 8, doi: 10.1007/s11783-023-1694-0

Abstract:

● Data quality assessment criteria for MP/NPs in food products were

Keywords： Microplastic     Nanoplastic     Food products     Data quality     Human health risk    

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Prospect in Creating New Drugs from Chinese Herbal Medicine

Yu Dequan

Strategic Study of CAE 1999, Volume 1, Issue 2,   Pages 87-90

Abstract: search for bioactive constituents or leading compounds from natural sources especially from Chinese herbalThis paper describes the progress in creating new drugs based on researches on natural products chemistry

The key point of study on the chemical constituents of individual Chinese herbal medicine hasStudy on the bioactive principle of Chinese herbal medicine involves an integration of chemical study

Keywords： natural product research     creating new drug     chemical constituent of Chinese herbal medicine     modem spectroscopic    

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An Empirical Study on the Internal Control Efficiency of Listed Engineering Companies

Zhi-wen Wang,Jing Tong

Frontiers of Engineering Management 2015, Volume 2, Issue 2,   Pages 159-164 doi: 10.15302/J-FEM-2015026

Abstract: This study presents an exploration of the relationship of independent director ratios, audit committee

Keywords： internal control efficiency     board of directors     independent directors     audit committee    

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Determination and occurrence of endocrine disrupting compounds, pharmaceuticals and personal care products

Yong YU,Laosheng WU

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 3,   Pages 475-481 doi: 10.1007/s11783-014-0640-6

Abstract: Endocrine disrupting compounds (EDCs), pharmaceuticals and personal care products (PPCPs) have attracted

Keywords： endocrine disrupting compounds (EDCs)     pharmaceuticals and personal care products (PPCPs)     fish     bisphenol    

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Integrated risk assessment framework for transformation products of emerging contaminants: what we know

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 7, doi: 10.1007/s11783-023-1691-3

Abstract:

● A better risk assessment can combine the improved non-target analysis method.

Keywords： Risk assessment frameworks     Transformation products     Emerging contaminants     High-throughput toxicity    

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Title Author Date Type Operation

The Globalization of Traditional Medicines: Perspectives Related to the European Union Regulatory Environment

Werner Knoess, Jacqueline Wiesner

Journal Article

The regulatory sciences for stem cell-based medicinal products

Bao-Zhu Yuan,Junzhi Wang

Journal Article

The South-to-North Water Diversion Project

Office of the South-to-North Water Diversion Project Construction Committee, State Council, PRC

Journal Article

IN VITRO ACTIVITY OF EXTRACTS OF FIVE MEDICINAL PLANT SPECIES ON PLANT PATHOGENIC FUNGI

Journal Article

An introduction to the medicinal plant genome project

Shilin Chen, Li Xiang, Xu Guo, Qiushi Li

Journal Article

Lingguizhugan Decoction, a Chinese herbal formula, improves insulin resistance in overweight/obese subjects

Journal Article

ACTIVITY OF EXTRACTS OF FIVE MEDICINAL PLANT SPECIES ON PLANT PATHOGENIC FUNGI

Shufeng YAO, Jiali XU, Haibo ZHANG, Hong GAO, Shibin SHANG, Dan WANG

Journal Article

Screening of indicator pharmaceuticals and personal care products in landfill leachates: a case study

Journal Article

Characteristics of typical dissolved black carbons and their influence on the formation of disinfection by-products

Journal Article

Antifungal and antibacterial functions of medicinal leech recombinant destabilase-lysozyme and its heated-up

T. G. YUDINA, Danyang GUO, N. F. PISKUNKOVA, I. B. PAVLOVA, L. L. ZAVALOVA, I. P. BASKOVA

Journal Article

Data quality assessment for studies investigating microplastics and nanoplastics in food products: Are

Journal Article

Prospect in Creating New Drugs from Chinese Herbal Medicine

Yu Dequan

Journal Article

An Empirical Study on the Internal Control Efficiency of Listed Engineering Companies

Zhi-wen Wang,Jing Tong

Journal Article

Determination and occurrence of endocrine disrupting compounds, pharmaceuticals and personal care products

Yong YU,Laosheng WU

Journal Article

Integrated risk assessment framework for transformation products of emerging contaminants: what we know

Journal Article